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5-Amino-1MQ
5-Amino-1MQ · Small molecule

5-Amino-1MQ
Research grade

Small-molecule NNMT inhibitor for preclinical research on fat metabolism and NAD+ balance

>99%
HPLC purity
3ml
BAC water included free
50mg
Lyophilizate

MOA: Used in research to study NNMT inhibition, fat metabolism and muscle stem cell function in animal models

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Choose quantity

69,99 €

per vial

✓ Includes 3 ml BAC water per vial — no need to order it separately

Volume discount: 3 % from 3 vials, 5 % from 5 vials, 10 % from 10 vials — pro rata in between, so 4 % for 4 vials. For larger quantities, ask us via the contact options below. No subscription, single purchase at any time.
Included: Every vial ships with 3 ml of bacteriostatic water at no extra charge. Additional BAC water (3 ml or 10 ml) can be ordered separately.
How to order: You can place a binding order right away — order number and payment details appear on the confirmation page immediately after submitting. Alternatively, send us your selection as a non-binding enquiry.
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HPLC-tested
COA on request
Plain packaging
24h discreet shipping
Secure payment

All prices incl. VAT · To the cart

Deep dive · research fields

What research is working on.

Used in research to study NNMT inhibition, fat metabolism and muscle stem cell function in animal models. For preclinical laboratory and research purposes only — no statement on use or effect.

NNMT inhibitorNicotinamide N-methyltransferaseNAD+AdipocytesMuscle stem cells
Literature

Selected studies

5-Amino-1-methylquinolinium is not a peptide but a small, membrane-permeable molecule from a class of nicotinamide N-methyltransferase (NNMT) inhibitors. It is used preclinically to study adipocyte metabolism, NAD+ and SAM flux and muscle regeneration.

  1. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

    Neelakantan H · Biochem Pharmacol · 2018 · PMID 29155147

    Membrane-permeable NNMT inhibitors of the methylquinolinium class in adipocytes and diet-induced obese mice; lower body weight and adipose mass were reported.

  2. Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

    Neelakantan H · Biochem Pharmacol · 2019 · PMID 30753815

    NNMT inhibition and activation of senescent muscle stem cells as well as regeneration after muscle injury in aged mice.

  3. Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice

    Sampson CM · Sci Rep · 2021 · PMID 33707534

    NNMT inhibitor combined with a reduced-calorie diet in obese mice; body composition, liver and adipose tissue metabolome were examined.

For preclinical laboratory and research purposes only — no statement on use or effect.

Purity story · batch 5-amino-1mq

From the lab to you. Documented.

Every batch is tested by HPLC; the result is in the batch COA.

1
Synthesis & HPLC >99%

Every batch independently tested by HPLC + MS

2
COA on request

Certificate of analysis on request

3
Traceability

Every batch clearly documented

4
Discreet 24h shipping

Plain packaging

5-Amino-1MQ
5-Amino-1MQ in the lab
Close-up of the lyophilizate
Aesthetic Peptides packaging with vial inlay
Product in detail Studio shots of the series.

Why Aesthetic Peptides

Every batch tested by HPLC. We send you the certificate of analysis (COA) for your batch on request.

Purity >99%
HPLC + MS analysis. Independent lab in Europe.
COA on request
COA on request
Traceability
Every batch clearly documented.
Discreet shipping 24h
Plain packaging, no identifying marks. Shipped within 24 hours of payment (business days).

Frequently asked questions

What is 5-Amino-1MQ?

Used in research to study NNMT inhibition, fat metabolism and muscle stem cell function in animal models

How is 5-Amino-1MQ stored?

Cool and dry at +4°C in the original packaging. Store protected from light.

Is a COA included?

We provide a certificate of analysis on request.

Legal disclaimer

5-Amino-1MQ is a research chemical intended exclusively for preclinical laboratory work and scientific studies. Not for human use, medical diagnosis, treatment or therapy. No recommendation for use. All products are offered "as is". GDPR-compliant.

5-Amino-1MQ
69,99 € per vial · incl. 3 ml BAC water
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